Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1988-04-08
1990-05-29
Draper, Garnette D.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
530395, 530404, 530402, 530405, 530412, 530413, 530414, 530415, 530416, 530416, 530418, 530419, 530422, 530820, 530825, 435 695, 435 696, 435 712, C07K 328
Patent
active
049297007
ABSTRACT:
A process for recovering dimeric, biologically active CSF-1 from bacterially expressed recombinant CSF1 genes is described. The process comprises recovery of the solubilized monomeric form, followed by dimerization under refolding conditions and further purification of the dimer. Heterodimers may also be produced by this process.
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Cowgill Cynthia
Halenbeck Robert
Koths Kriston
Laird Walter J.
Cetus Corporation
Draper Garnette D.
Halluin Albert P.
McLaughlin Jane R.
Murphy Lisabeth F.
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