Synthetic oligomers having chirally pure phosphonate internucleo

Details Synthetic oligomers having chirally pure phosphonate internucleo Synthetic oligomers having chirally pure phosphonate internucleo

1994-11-21

2000-02-22

Houtteman, Scott W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 221, 536 245, C07H 2104

Patent

active

06028188&

ABSTRACT:
Oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages which hybridize to RNA target sequences and methods for their preparation are provided.

REFERENCES:
patent: 4358535 (1982-11-01), Falkow et al.
patent: 5212295 (1993-05-01), Cook
patent: 5403711 (1995-04-01), Walder et al.
patent: 5457026 (1995-10-01), Dreyfuss et al.

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