Substituted thiophene-2-sulfonamide antiglaucoma agents

Details Substituted thiophene-2-sulfonamide antiglaucoma agents Substituted thiophene-2-sulfonamide antiglaucoma agents

1988-12-14

1990-05-29

Siegel, Alan

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514252, 514256, 514336, A61K 3138

Patent

active

049296370

ABSTRACT:
Thiophene-2-sulfonamides with an alkyl or substituted-alkyl and an alkyl-S(O).sub.n -substituent are carbonic anhydrase inhibitors useful in the treatment of elevated intraocular pressure.

REFERENCES:
patent: 4386098 (1983-05-01), Woltersdorf
patent: 4416890 (1983-11-01), Woltersdorf
patent: 4426388 (1984-01-01), Woltersdorf
patent: 4542152 (1985-09-01), Shepard
patent: 4619939 (1986-10-01), Maren
patent: 4721794 (1988-01-01), Shepard
Kremlev, Chem. Abstr. 81, 120357r (1974).

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