Tetrahydropyridine isoxazoline derivatives

Details Tetrahydropyridine isoxazoline derivatives Tetrahydropyridine isoxazoline derivatives

1992-03-24

1994-07-19

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514326, 546275, 546208, C07D40104, A61K 3144

Patent

active

053309944

ABSTRACT:
A novel compound of the following formulas useful in treating immune-related diseases, inflammation, stoke, epilepsy, dystonias, psychoses, anxiety, and depression: ##STR1##

REFERENCES:
The Condensed Chemical Dictionary 10th Edition by Hawley, p. 90, 1981.
Clark et al. Principles of Psychopharmacology 1970, pp. 166-167.
Trends in Neuroscience, 10(11):444-446 (1987), Quirion et al., "Classification and nomenclature of phencyclidine . . . ".
Clinical Neuropharmacology, 11(2):105-119, S. Deutsch et al., "The Sigma Receptor: A Novel Site Implicated . . . ".
Molecular Pharmacology, 32:772-784, (1987), B. Largent et al., "Structural Determinants of .sigma. Receptor Affinity".
Pharmacological Reviews, 42(4):355-402, (1990), J. Walker, et al., "Sigma Receptors: Biology and Function".
Drug Development Research, 11:65-70 (1987), D. Taylor et al., "Potential Antipsychotic BMY 14802 Selectively . . . ".
Clinical Neuropharmacology, 11(6):565, (1988), K. Jansen, "The Sigma Receptor and Movement Disorders".
Neurology, 38:961-965 (1988), J. Walker et al., "Evidence for a role of haloperidol-sensitive .sigma.-`opiate` . . . ".
European J. of Pharmacology, 147:153-154 (1988), W. Bowen et al., "Altered haloperidol-sensitive .sigma. receptors . . . ".
Science, 2240:219-221 (1988), T. Su et al., "Steroid Binding at .sigma. Receptors Suggest a Link Between . . . ".
European J. of Pharmacology, 148:467-470 (1988), T. Su et al., "Correlation of inhibitory potencies of putative . . . ".
Soc. for Neuroscience Abstracts, 13(2):1437 (1987), S. Wolfe et al., "Sigma Receptors in Human Peripheral . . . ".
J. Pharmacology and Experimental Therapeutics, 197(3):517-532, W. Martin et al., "The Effects of Morphine . . . ".
Society for Neuroscience Abstracts, 17:333 (1991), L. Cook et al., "The Pharmacology of a Sigma . . . ".

Affiliated with

Also associated with

Rating

Tetrahydropyridine isoxazoline derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tetrahydropyridine isoxazoline derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tetrahydropyridine isoxazoline derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-520216