Substituted urea compounds and their preparation and use

Details Substituted urea compounds and their preparation and use Substituted urea compounds and their preparation and use

1992-09-17

1994-07-19

Mars, Howard T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514304, 546112, 546124, 546125, A61K 3144, C07D22102

Patent

active

053309901

ABSTRACT:
New substituted urea compounds of formula I, or a pharmaceutically acceptable salt thereof: ##STR1## wherein R.sup.1 is a group of formula II, III or IV ##STR2## where n is 2 or 3, p is 1 or 2, q is 1 to 3, r is 1-3 and R.sup.4 and R.sup.5 are H, C.sub.1-7 alkyl or C.sub.3-6 cycloalkyl; and wherein R.sup.2 is an oxadiazole, substituted with C.sub.1[ alkyl, C.sub.2-8 alkenyl, C.sub.2-8 alkynyl, C.sub.3-7 cycloalkyl, benzyl, phenyl, C.sub.1-6 alkoxy, C.sub.1-6 alkylthio, amino or alkylamino; or

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