Process for the optical resolution of the dl-.alpha.-hydroxy-3-(

Details Process for the optical resolution of the dl-.alpha.-hydroxy-3-( Process for the optical resolution of the dl-.alpha.-hydroxy-3-(

1983-10-07

1985-08-06

Bond, Robert T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

2602393B, C07D28102, C07C14920

Patent

active

045337489

ABSTRACT:
The dl-.alpha.-2-hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, which is a useful intermediate for the synthesis of pharmacologically active compounds, is separated in its enantiomers through salification with L-lysine with high yields and optical purities.

REFERENCES:
Chemical Abstracts I vol. 74: 141721(a), Abstracting Kugita et al., "Chem. Pharm. Bull." (1971), vol. 19, No. 3, pp. 595-602.
Chemical Abstracts II vol. 90: 6431(w), Abstracting Japan Tokyo Koho 78 18,038 Jun. 13, 1978.

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