Indolylalkyl derivatives of pyrimidinylpiperazine for treating v

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544295, A61K 31505, C07D40300

Patent

active

053005066

ABSTRACT:
A series of novel indol-3-ylalkyl derivatives of alkoxypyrimidinylpiperazines are disclosed as Formula I. ##STR1## These compounds are intended to be useful agents for alleviation of vascular headache on the basis of their potent affinity and agonist activity at 5-HT1D binding sites.

REFERENCES:
patent: 3188313 (1965-06-01), Archer
patent: 3562278 (1971-02-01), Archer
AMA Drug Evaluations 6th Edition, 1986, pp. 239-253 W.B. Saunders Co., Philadelphia, Pa.

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