Apparatus for immunological analysis

Details Apparatus for immunological analysis Apparatus for immunological analysis

1997-01-10

1998-05-05

Alexander, Lyle A.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Sample mechanical transport means in or for automated...

422 72, 422102, G01N 2107

Patent

active

057469750

ABSTRACT:
The apparatus of the invention is in the form of a kit comprising two distinct elements designed to be assembled together and to co-operate during immunological analysis. The first element is an incubation element that includes at least one receptacle suitable for receiving a mixture comprising a substance to be analyzed and a test substance. The second element is a reaction element and includes at least one well which is closed by a sealing membrane and which has a bottom on which a reactionally sensitive layer is fixed. The apparatus includes means for assembling said elements together and perforation and injection means, e.g. a tapering tube, projecting from the bottom of the receptacle of the incubation element and extending outwards, said means being suitable firstly for perforating the membrane and then for injecting the contents of the receptacle into the well through said perforated membrane, once the two elements have been assembled together. The method consists in assembling the two elements together so that the tapering tube perforates the membrane and penetrates into the well, in incubating them, and then in centrifuging them at a speed sufficient to cause the mixture to pass from the receptacle into the well via the tapering tube.

REFERENCES:
patent: 3825410 (1974-07-01), Bagshawe
patent: 4252538 (1981-02-01), Barr
patent: 5149501 (1992-09-01), Babson et al.

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