N-substituted azaheterocyclic compounds

Details N-substituted azaheterocyclic compounds N-substituted azaheterocyclic compounds

1997-10-03

1999-12-21

Shah, Mukund I.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514211, 514217, 5142255, 514320, 514324, 514422, 514428, 540550, 540591, 544 46, 546195, 546196, 548525, 548528, A61K 3140, A61K 31445, C07D20708, C07D21134

Patent

active

060049839

ABSTRACT:
The present invention relates to novel N-substituted azaheterocyclic carboxcylic acids of the general formula wherein X, Y, Z, R.sup.1, R.sup.2 and r are as defined in the detailed part of the description, or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation as well as their use for treatment of indications caused by or related to the secretion and circulation of insulin antagonising peptides.

REFERENCES:
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patent: 5688788 (1997-11-01), Andersen et al.
patent: 5712292 (1998-01-01), Andersen et al.
patent: 5716949 (1998-02-01), Andersen et al.
patent: 5721254 (1998-02-01), Andersen et al.
Sindelar et al., Collect. Czech. Chem. Commun., vol. 59, pp. 667-674, (1994).

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