Anti-atherosclerotic indolizine derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546112, A61K 31435, C07D47104

Patent

active

047512350

ABSTRACT:
7-(indolizin-2-yl)hept-6-enoic acids of the formula I: ##STR1## wherein each of R.sup.1 and R.sup.2 is, independently, H, alkyl, cycloalkyl, aralkyl or aryl, ##STR2## in which R.sup.8 is H, an ester residue or cation; or the lactone thereof. The compounds are useful as hypocholesteremic agents.

REFERENCES:
patent: 4248889 (1981-02-01), Oka et al.
patent: 4255444 (1981-03-01), Oka et al.
patent: 4375475 (1983-03-01), Willard et al.
patent: 4474971 (1984-10-01), Wareing
patent: 4520026 (1985-05-01), Rosseels et al.

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