Substituted thieno[2,3-b]pyrrole-5-sulfonamides as antiglaucoma

Details Substituted thieno[2,3-b]pyrrole-5-sulfonamides as antiglaucoma Substituted thieno[2,3-b]pyrrole-5-sulfonamides as antiglaucoma

1987-09-16

1988-06-14

Siegel, Alan

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514253, 514321, 5142338, 544144, 544373, 546198, 548453, A61K 31445, C07D48702

Patent

active

047512318

ABSTRACT:
Thieno[2,3-b]pyrrole-5-sulfonamides are carbonic anhydrase inhibitors useful in the treatment of elevated intraocular pressure and glaucoma.

REFERENCES:
patent: 4477466 (1984-10-01), Shepard
patent: 4668697 (1987-05-01), Shepard
Snyder et al., J. Amer. Chem. Soc., 1957, 79, 2556.
Kumar et al., Ind. J. Chem., 1981, 20B, 271.

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