Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Peptides containing saccharide radicals – e.g. – bleomycins – etc.
Patent
1991-05-03
1995-07-11
Kim, Kay K. A.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Peptides containing saccharide radicals, e.g., bleomycins, etc.
530345, 530377, 530395, 530402, 530403, 436518, 435188, 4241931, C07K 900, C07K 1700, A61K 3814, A61K 39385
Patent
active
054322600
ABSTRACT:
Polypeptide backbones containing sugar residues at repetitive intervals are capable of binding the mannose receptor when said sugars are mannosyl, fucosyl, or N-acetyl glucosamine residues. These peptides are of the formula
REFERENCES:
patent: 4386026 (1983-05-01), Ponpipom et al.
patent: 4946675 (1990-08-01), Baldwin et al.
patent: 5028594 (1991-07-01), Carson
Crocker et al., J. Exp. Med. (1986) 164:1862-1875.
Aminoff et al., Proc. Natl. Acad. Sci. (1977) 74:1521-1524.
Schlepper-Schaffer et al., Biochem. Biophys. Res. Commun. (1983) 115:551-559.
De May et al., Proc. Natl. Acad. Sci. (1978) 75:1339-1343.
Lennartz et al., J. Biol. Chem. (1989) 264:2385-2390.
Lennartz et al., J. Biol. Chem. (1987) 262(21):9942-9944.
Taylor et al., J. Biol. Chem. (1990) 265(21):12156-12162.
Ezekowitz et al., J. Cell. Sci. (1988) Suppl. 9:121-133.
Stahl et al., Cell (1980) 19:207-215.
Ponipom et al., J. Med. Chem. (1981) 24:1388-1395.
Wileman et al; PNAS (USA) 83:2501-2505 Apr. 7, 1986.
Westcott et al; J. Biol. Chem. 262(13):6101-6107 (1987).
Tong et al; J. Biol. Chem. 264(14):7962-7969 (May 15, 1989).
Dong et al; J. Biol. Chem. 265(8):4210-4217 (Mar. 15, 1990).
Chao et al; EMBO J. 9(11):3507-3513 (Nov. 1990).
Li et al; J. Biol. Chem. 266(26):17621-17630 (Sep. 15, 1991).
Taylor et al; J. Biol. Chem. 267(3):1719-1726 (Jan. 25, 1992).
Rogers et al; J. Biol. Chem. 265(17):9722-9727 (Jun. 15, 1990).
Doebber et al; J. Biol. Chem. 257(5):2193-2199 (Mar. 10, 1982).
Hoppe et al; Biochemistry 23:1723-1730 (1984).
MacDonald, et al., J. Biol. Chem. (1989) 264(6):3256-3261.
Kim Kay K. A.
Washington University
LandOfFree
High affinity mannose receptor ligands does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with High affinity mannose receptor ligands, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and High affinity mannose receptor ligands will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-504201