Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Inactivation or attenuation; producing viral subunits
Patent
1997-03-05
1999-12-21
Stucker, Jeffrey
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
Inactivation or attenuation; producing viral subunits
4241921, 4242081, 435 5, 4351723, 536 231, C12N 704, A61K 3900, C12Q 170, C07H 2102
Patent
active
060047992
ABSTRACT:
This invention discloses live-attenuated feline immunodeficiency virus (FIV), and recombinant vectors for producing them, useful as vaccines and therapeutic agents against FIV and diseases associated with virulent FIV infection. In the recombinant vectors and FIVs, one or more genes, or part of the gene(s), responsible for FIV pathogenesis have been completely or partially rendered nonfunctional, e.g., by full or partial deletion or mutagenesis. These anti-FIV vaccines may be given to susceptible hosts in the form of infectious virus or cloned DNA.
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Luciw Paul A.
Sparger Ellen E.
Park Hankyel T.
Stucker Jeffrey
The Regents of the University of California
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