Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1998-05-20
1999-12-21
Arthur, Lisa B.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 9121, 435 912, C12Q 168, C12P 1934
Patent
active
060047569
ABSTRACT:
A purified and isolated DNA sequence and the encoded mammary-specific protein, mammaglobin, are disclosed. Also disclosed are methods for the detecting breast cancer based upon the overexpression and secretion of mammaglobin by breast cancer cells. The methods detect and/or quantitate the presence of mammaglobin or the mRNA encoding mammaglobin.
REFERENCES:
patent: 5668267 (1997-09-01), Watson et al.
patent: 5855889 (1999-01-01), Watson et al.
Becker et al. Genomics (1988 Nov. 15) 54(1):70-8.
Watson et al. Oncogene (1998 Feb. 12) 16(6):817-824.
Watson et al. Cancer Res. (1996 Feb. 15) 56(4) 860-4.
Leygue et al. Breast Cancer Res & Treatment (Oct. 1997) vol. 46, No. 1, p. 44.
Bjork et al, Partial Characterization and "Quantitation" of a Human Prostatic Estramustine-binding Protein, Cancer Res. 42:1935-1942 (1982).
Bjork et al., Expression and Partial Characterization of Estramustine-Binding Protein IEMBP) in Human Breast Cancer and Malignant Melanoma, Anticancer Res. 11:1173-1182 (1991).
Cato et al., The Hormonal Regulation of Uteroglobin Gene Expression, Anticancer Res. 4:65:72 (1985).
Miele et al., Uteroglobin: Structure, Molecular Biology, and New Perspectives on its Function as a Phospholipase A.sub.2 Inhibitor, Endocrine Rev. *:474-490 (1987).
Miele et al., Uteroglobin and uteroglobin-like proteins: The uteroglobin family of proteins, J. Endocrinol. Invest. 17:679-692 (1994).
Parker et al., Prostatic Steroid-binding Protein, J. Biol. Chem. 258:12-15 (1983).
Parker et al., Organization and Expression of Prostatic Steroid Binding Protein Genes, J. Steroid Biochem. 20:67-71 (1984).
Parker et al., Organization and Expression of Genes Encoding Prostatic Steroid Binding Protein, Ann N.Y. Acad. Sci. 438:115-124 (1984).
Peeters et al., Structural Studies on Rat Prostatic Binding Protein, Eur. J. Biochem. 115:115-121 (1981.
Peri et al., Tissue-specific Expression of the Gene Coding for Human Clara Cell 10-kD Protein, a Phospholipase A.sub.2 -inhibitory Protein, J. Clin. Invest. 92:2099-2109 (1991).
Watson et al., Isolation of Differentially Expressed Sequence Tags from Human Breast Cancer, Cancer Res. 54:4598-4602 (1994).
Fleming Timothy P.
Watson Mark A.
Arthur Lisa B.
Washington University
LandOfFree
Method for detecting the presence of breast cancer by detecting does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for detecting the presence of breast cancer by detecting , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for detecting the presence of breast cancer by detecting will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-503632