Compounds having cholecystokinin and gastrin antagonistic proper

Details Compounds having cholecystokinin and gastrin antagonistic proper Compounds having cholecystokinin and gastrin antagonistic proper

1991-05-08

1994-08-23

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 19, 514210, 514212, 514315, 514410, 514411, 514423, 530330, 530331, 540606, 540607, 546244, 546245, 548492, 548538, A61K 3140, A61K 3743, C07K 506, C07K 508

Patent

active

053408012

ABSTRACT:
This invention relates to N-arylcarbamoyl proline analogues which are useful as cholecystokinin and gastrin antagonists, to pharmaceutical compositions including such proline analogues, and to their use in preventing or treating cholecystokinin or gastrin related disorders.

REFERENCES:
patent: 3886177 (1975-05-01), Fontanella et al.
patent: 4357471 (1982-11-01), Smolanoff
patent: 4559339 (1985-12-01), Bock et al.
patent: 4684646 (1987-08-01), Chang et al.
patent: 4692522 (1987-09-01), Parsons et al.
patent: 4757068 (1988-07-01), Parsons
patent: 4812452 (1989-03-01), Shanklin, Jr. et al.
patent: 4820834 (1989-04-01), Evan et al.
patent: 4847248 (1989-07-01), Freidinger et al.
patent: 4880938 (1989-11-01), Freidinger et al.
patent: 4910190 (1990-03-01), Bergeson et al.
patent: 5075313 (1991-12-01), Yu et al.
patent: 5162336 (1992-11-01), Molino et al.
Eur. J. Pharm., vol. 162 issued 1989, Lotti et al., "A New potent and selective non-peptide gastrin . . . ", pp. 273-280.
PNAS, vol. 78, No. 10, issued Oct. 1981, Hahne et al., "Proglumide and benzotript . . . ", 6304-6308.
J. Med. Chem., vol. 31, issued 1988, Evans et al., "Methods for Drug Discovery . . . ", pp. 2235-2246.
Japan J. Pharmacol., vol. 46, issued 1988, Itonaga et al., "Cholecystokinin Antagonism . . . ", pp. 319-324.
J. Med. Chem., vol. 25, issued 1982, Cain et al., ".beta.-Carbolines: Synthesis and Neurochemical . . . ", pp. 1081-1091.
Heterocycles, vol. 22, No. 1, issued 1984, Coutts et al., "Some 3-Carboxamides of .beta.-Carboline . . . ", p. 131.
U.S. patent application Ser. No. 07/542,295.
U.S. patent application Ser. No. 07/573,514.
Chemical Abstract 94:156735v (1980).

Affiliated with

Also associated with

Rating

Compounds having cholecystokinin and gastrin antagonistic proper does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds having cholecystokinin and gastrin antagonistic proper, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds having cholecystokinin and gastrin antagonistic proper will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-503128