Tetrazole derivatives, and anti-ulcer composition containing the

Details Tetrazole derivatives, and anti-ulcer composition containing the Tetrazole derivatives, and anti-ulcer composition containing the

1981-02-27

1983-02-08

Ford, John M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546209, 42424851, 546210, 546212, 42424852, 546256, 546172, 42424856, 546176, 546284, 42424857, 546276, 548202, 424251, 548203, 548214, 424258, 548252, 548253, 424272, 548136, 548143, 424273R, 548204, 548205, 424273B, 548254, 548250, 424263, 548251, 424270, 424269, 544132, 544124, 544131, 544122, 544128, 544134, 544138, 544133, 544119, 544357, 544360, 544363, 544366, 544367, 544333, 2602433, 2602455_, 546193, 546201, 546208, A61K 3141, A61K 3144, A61K 31445, A61K 31505, C07D25704, C07D40112, C07D40114, C07D

Patent

active

043729533

ABSTRACT:
Tetrazole derivatives of the formula: ##STR1## wherein R.sup.1 is a lower alkykl, phenyl or a group of the formula: --S(O).sub.l --A--(X).sub.m --R.sup.3, and R.sup.2 is hydrogen, a lower alkyl, phenyl or a cycloalkyl when R.sup.1 is the group --S(O).sub.l --A--(X).sub.m --R.sup.3, or R.sup.2 is a group of the formula: --B--CO--R.sup.4 when R.sup.1 is a lower alkyl or phenyl and a pharmaceutically acceptable salt thereof, which have prophylactic or therapeutic activities against peptic and/or duodenal ulcers and are useful as an anti-ulcer drug; processes for the preparation of the tetrazole derivatives; and pharmaceutical composition containing said tetrazole derivatives.

REFERENCES:
patent: 2507337 (1950-05-01), Harvill et al.
patent: 3578674 (1971-05-01), Buckler
patent: 3743646 (1973-07-01), Buckler et al.
patent: 3767667 (1973-10-01), Wehrli
patent: 4110338 (1978-08-01), Kamiya
LaForge et al., J. Org. Chem., vol. 21, pp. 767-771 (1956).

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