Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)

Details Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl) Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)

1982-09-30

1984-03-13

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

548336, A61K 31415, C07D40304

Patent

active

044367465

ABSTRACT:
Various 1-carboxylic acid substituted-2-(1-imidazolyl)indoles and functional derivatives thereof are highly specific thromboxane synthetase inhibitors. Synthesis of, pharmaceutical compositions thereof, and methods of treatment utilizing such compounds are included.

REFERENCES:
patent: 3454586 (1969-07-01), Suh
patent: 4059583 (1977-11-01), McComsey et al.
patent: 4140858 (1979-02-01), Zinnes et al.
patent: 4217357 (1980-08-01), Cross et al.
patent: 4273782 (1981-06-01), Cross et al.
Abstracts, North American Medicinal Chemistry Symposium (1980), p. 68.

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