Phosphine oxides having a physiological cooling effect

Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid

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131120, 132 89, 252 325, 252522, 424 49, 424 57, 424 65, 424 70, 424 73, 424148, 424156, 424168, 424198, 424230, 424329, 424358, 426 3, 426590, A61K 3166, A61K 716

Patent

active

040704963

ABSTRACT:
Compounds and compositions are disclosed having a physiological cooling action on the skin. The compositions contain as the active ingredient certain phosphine oxides. The compositions disclosed include toilet and cosmetic preparations, e.g. toilet water, after-shave lotions, soaps, cosmetic creams and lotions, dentifrices and cleansing tissues, and tobacco and tobacco preparations.

REFERENCES:
patent: 3158461 (1964-11-01), Weil
patent: 3304263 (1967-02-01), Yoke et al.
patent: 3326768 (1967-06-01), MacMillan
patent: 3331878 (1967-07-01), Priestley
patent: 3338701 (1974-05-01), Weil
patent: 3644653 (1972-02-01), Tcheiltcheff
Chemical Abstracts, 7th Collective Index, (1962-1966), vols. 56-65, pp. 13780s-13782s.
Chemical Abstracts, 8th Collective Index, (1967-1971), vols. 66-75, pp. 18623s-18627s.
Wilson et al., Textbook of Organic Medicinal and Pharmaceutical Chemistry, 4th Edition, (1962), pp. 111-112.
Remington's Pharmaceutical Sciences, 13th Edition, (1965), p. 855.

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