Derivatives of 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic ac

Details Derivatives of 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic ac Derivatives of 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic ac

1976-12-13

1978-01-24

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D49104

Patent

active

040703711

ABSTRACT:
Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole or 1,3,4,9-tetrahydrothiopyrano[3,4-b]indole nucleus bearing a substituent in position 1, said substituent incorporating an acid, ester or amide function therein, are disclosed. The nucleus is further substituted at position 1 and may be optionally substituted at positions 3, 4, 5, 6, 7, 8, and 9. The derivatives are useful antiinflammatory, analgesic, antibacterial and antifungal agents and methods for their preparation and use are also disclosed.

REFERENCES:
patent: 3939178 (1976-02-01), Demerson et al.

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