Piperazinylbenzodioxane derivatives

Details Piperazinylbenzodioxane derivatives Piperazinylbenzodioxane derivatives

1992-08-24

1993-09-07

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544370, 544373, 544377, A61K 31495, C07D40314

Patent

active

052429253

ABSTRACT:
Piperazinylbenzodioxane derivatives of formula I ##STR1## wherein B is an indol-3-yl or benzimidazol-1-yl radical which is unsubstituted or monosubstituted by CN, CO--R.sup.1, C.sub.n H.sub.2n --R.sup.1, Hal, OH, OA, O--C.sub.n H.sub.2n --CO--R.sup.1, or NHR.sup.2, and Q is C.sub.n H.sub.2n, or a physiologically acceptable salt thereof. The derivatives are active in the central nervous system, especially as serotonin agonists and antagonists.

REFERENCES:
patent: 3135794 (1964-06-01), Archer
patent: 4448777 (1984-05-01), Heinemann et al.
patent: 4684651 (1987-08-01), Kikumoto et al.

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