Method and system for generating and collecting gallium-68 using

Chemistry of inorganic compounds – Treating mixture to obtain metal containing compound – Radioactive metal

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250432PD, 424 1, G01N 2312, C01G 1500, A61K 4300, A61K 4900

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active

043305075

ABSTRACT:
A method for generating Ga-68 from Ge-68 is provided that comprises contacting a substrate on which Ge-68 has been adsorbed with an alkaline solution having a pH of at least about 12 and thereby eluting Ga-68. Preferably the Ga-68 is eluted in the form of the gallate ion. A generator system comprises a generator column containing Ge-68 and Ga-68, a sealed eluant container having a predetermined quantity of eluant comprising an alkaline solution having a pH of at least about 12, and an evacuated eluate collection vial having a vacuum sufficient to draw the desired quantity of eluate into the eluate collection vial. The eluate collection vial can contain a neutralizing agent and also a diagnostically useful complexing agent.

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