Compositions, processes and method

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Other Related Categories

26050117, 26050118, 26050119, 564349, 424316, A01N 3302, A01N 3730

Type

Patent

Status

active

Patent number

043966292

Description

ABSTRACT:
Therapeutically useful 1-(substituted-amino)-3-[4-R.sub.1 O-3-(lower-alkylthio, lower-alkylsulfinyl or lower-alkylsulfonyl)phenoxy]-2-propanols are obtained by reacting a 4-R.sub.1 0-3-(lower-alkylthio, lower-alkylsulfinyl or lower-alkylsulfonyl)phenol with an epihalohydrin and reacting the resulting product with a primary amine. The compounds have both antihypertensive and .beta.-adrenergic blocking activity and are useful as antihypertensive agents.

REFERENCES:
patent: 3501769 (1970-03-01), Crowther et al.
patent: 3542874 (1970-11-01), Keizer et al.
patent: 3712890 (1973-01-01), Lee
patent: 3732308 (1973-05-01), Lauria et al.
patent: 3872147 (1975-03-01), Koppe et al.
patent: 4067904 (1978-01-01), Comer et al.
patent: 4085136 (1978-04-01), Tucker
patent: 4243681 (1981-01-01), Morrow et al.
patent: 4244969 (1981-01-01), Carlsson et al.
Burger, "Medicinal Chemistry", 3rd. Ed., Part II, pp. 1052-1055 (1970).
Kalser et al., "Journ. Med. Chem.", vol. 18, No. 7, pp. 674-683 (1975).
Hoefle et al., "Journ. Med. Chem.", vol. 18, pp. 148-152 (1975).
L. Villa et al., Il Farmaco, Ed. Sci., 24, 349-357 (1969).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compositions, processes and method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions, processes and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions, processes and method will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-483913

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.