Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1978-09-13
1979-09-11
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
26065E, A61K 31275, C07C12168
Patent
active
041675800
ABSTRACT:
This disclosure describes compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease, and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the active ingredients of said compositions of matter being benzimidoylacetonitrile, meta-fluorobenzimidoylacetonitrile, para-fluorobenzimidoylacetonitrile, or mixtures thereof.
REFERENCES:
lang, et al., J. Med. Chem 18, 441 (1975).
American Cyanamid Company
Conroy, Jr. Edward A.
Friedman Stanley J.
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