Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1987-05-11
1989-03-21
Daus, Donald G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D49812, A61K 3133, A61K 31445
Patent
active
048144495
ABSTRACT:
Disclosed are a compound of the general formula ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each represents a hydrogen atom, an alkyl group or an acyl group, process for the production thereof and use thereof. The compounds have an antitumor activity, and those wherein both of R.sub.1 and R.sub.2 represent a hydrogen atom or an acyl group are novel compounds.
REFERENCES:
Omura et al., CA 106-4725v, (1987), "Structure of Cervinomycin; a Novel Antianaerobic Antibiotic".
Nakagawa et al., CA 106-81432z, (1987), "Enhanced Antimicrobial Activity of Acetyl Derivatives of Cervinomycin".
Nakagawa et al., CA 107-217314t, (1987), "Structure of Cervinomycin, a Novel Xanthone Antibiotic Active Against Anaerobes and Mycoplasma".
The Journal of Antibiotics, vol. XXXV, No. 6, (1982), pp. 645-652.
Proceedings of 106th Congress of Japanese Pharmacological Society held on Apr. 2-4, 1986, p. 207, 4S 10-3 by A. Nakagawa et al.
Proceedings of 106th Congress of Japanese Pharmacological Society held on Apr. 2-4, 1986, p. 489, 3E 10-3, by Y. Shimizu et al.
J. Am. Chem. Soc., 108, (1986), 6088-6089, by Omura et al., Sep. 1986.
The Journal of Antibiotics, vol. XXXIX, No. 11, (1986), 1636-1637, by A. Nakagawa et al.
The Journal of Antibiotics, vol. XL, No. 3, (1987), pp. 301-308, by Omura et al.
Chang-qing Qi
Jie Tian
Marunaka Teruyoshi
Minami Yoshinori
Ohtani Toshio
Daus Donald G.
Shen Cecilia
Taiho Pharmaceutical Company Limited
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