Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents

Details Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents

1989-01-24

1990-03-06

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514428, 548525, 548528, C07D40502, C07D29512, A61K 3140

Patent

active

049066552

ABSTRACT:
Novel 1,2-cyclohexylaminoaryl amides useful as analgesic agents having very high kappa-opioid affinity and selectivity and potency and useful as analgesics, diuretics, antiinflammatory and psychotherapeutic agents are disclosed. Methods for making the compounds and pharmaceutical compositions containing them are also disclosed.

REFERENCES:
patent: 4145435 (1979-03-01), Szmuszkovicz
patent: 4438130 (1984-03-01), Kaplan
patent: 4463013 (1984-07-01), Collins et al.
patent: 4656182 (1987-04-01), Horwell
patent: 4738981 (1988-04-01), Horwell

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