Production of loaded vesicles

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435182, 436528, 436829, 264 4, 264 43, 264 46, 514 2, G01N 33544

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active

048142700

ABSTRACT:
Vesicles having a material encapsulated therein are produced by placing an "empty" vesicle in a liguid including a material to be encapsulated and perturbing the vesicle, preferable by passage through a porous material.

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Olson, et al, "Preparation of Liposomes of Defined Size Distribution by Extrusion Through Polycarbonate Membranes", Biochimica et Biophysica Acta, 557, pp. 9-23 (1979).
Reeves, et al, "Formation and Properties of Thin-Walled Phosphollipid Vesicles", J. Cell. Physiol., vol. 73, pp. 49-60 (1969).
Morris, "Liposomes as a Model System for Investigating Freezing Injury, Effects of Low Temperature on Biological Membranes," pp. 241-262, Acad. Press (1981).

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