Method for treating pertussis

Drug – bio-affecting and body treating compositions – Lymphokine

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514 8, 514 23, 514 62, 514 54, 436547, 530397, A61K 3170, A61K 39395, A61K 3704

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046613455

ABSTRACT:
Method of inhibiting the adhesion of Bordetella pertussis to the cilia of human respiratory cells to treat pertussis, agents and compositions useful in the method. Agents are also useful to stimulate the production of antibodies.

REFERENCES:
Tuomanen et al, "Characterization of Antibody Inhibiting . . . Cells", J. Clinical Microbiol. vol. 20(2) 1984, pp. 167-170.
Sato et al, "Affinity of Pertussis Toxin Produced by Bordetella-Pertussis . . . Toxin", J. Microbial Methods 1(2) 1983, pp. 99-110 (abstract).
Sato et al, "Monoclonal Antibody Against Pertussin Toxin:" Infect and Immunity 46(2) 1984, pp. 422-428.
Tuomanen et al, "Adherence of B. pertussis to . . . Cells," J. of Infect. Disease, vol. 148(1) 1983, pp. 125-130.
Irons et al, "Isolation of the LP Factor . . . Affinity Chromatography"; Biochim Biophys Acta 580, 1979, pp. 175-185.
Iwata et al, "Modulation of the Biological Activities of IgE-Binding Factor", J. Immunol, vol. 130(4) 1983, pp. 1802-1808.

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