Carboxyalkyl dipeptides as antiglaucoma agents

Details Carboxyalkyl dipeptides as antiglaucoma agents Carboxyalkyl dipeptides as antiglaucoma agents

1988-07-18

1990-03-06

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544 6, 544 13, A61K 31505

Patent

active

049066358

ABSTRACT:
Methods and pharmaceutical compositions are disclosed for reducing intraocular pressure. The methods and compositions employ an active ingredient which comprises certain benzothiadiazinyl and quinazolinyl substituted carboxyalkyl dipeptides wherein the benzothiadiazinyl or quinazolinyl portions are joined to the dipeptide portions by an aminocarbonyl group.

REFERENCES:
patent: 3539564 (1970-11-01), Shetty
patent: 3549629 (1970-12-01), Shetty
patent: 3549636 (1970-12-01), Shetty
patent: 3816631 (1974-06-01), Novello
patent: 4338435 (1982-07-01), Haugwitz
patent: 4376768 (1983-03-01), Ozaki et al.
patent: 4431645 (1984-02-01), Smith et al.
patent: 4451467 (1984-05-01), Ishikawa et al.
patent: 4468396 (1984-08-01), Magatti
patent: 4551452 (1985-11-01), Marfat
patent: 4681886 (1982-07-01), Haugwitz et al.
44,892/59--Jan. 8, 1959--Merck & Co.--Section 43 of Pat. Act. 1952-1955--Publication.
Abstract of European Patent Application 95584--Dec. 1983, (see AK above).
Abstract of Australian Patent Application 8,313,837, Nov. 1983, (see AK above).

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