Pyrazine amides

Details Pyrazine amides Pyrazine amides

1988-05-26

1990-03-06

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544407, A61K 31495, C07D24120

Patent

active

049066331

ABSTRACT:
Novel pyrazine amides of Formula III (set out hereinafter) are disclosed which are useful as eukalemic diuretics.

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Stokker, G. E., et al., J. Med. Chem., 1980, 23, 1414-1427.
Edward J. Cragoe, Jr., Diuretics Chemistry, Pharmacology, and Medicine, (1983) 268-302: "2-Aminomethylphenols: A New Class of Saluretic Agent".
Cragoe, Jr., Diuretics, Chemistry, Pharmacology, and Medicine, pp. 268-302 (1983).

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