Isomorphic copolyoxalates and sutures thereof

Details Isomorphic copolyoxalates and sutures thereof Isomorphic copolyoxalates and sutures thereof

1978-06-14

1980-06-17

Phynes, Lucille M.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

From carboxylic acid or derivative thereof

3 1, 3 14, 3 15, 128 92B, 128 92C, 128334R, 1283355, C08G 6318

Patent

active

042085110

ABSTRACT:
Synthetic absorbable sutures are prepared from copolyoxalate polymers having isomorphic sequences. The polymers are derived from mixtures of cyclic and linear diols, each having the same carbon chain length of 6 or 8 atoms. The cyclic diol may be aliphatic or aromatic. The diols are polymerized with dialkyl oxalate, preferably in the presence of an inorganic or organometallic catalyst, to obtain a highly crystalline isomorphic copolyoxalate polymer which is melt extruded and drawn to form oriented filaments. The filaments are characterized by good initial tensile and knot strength and a high order of softness and flexibility. When implanted in living animal tissue, the fibers have good strength retention over a period of at least 21 days and eventually absorb with a minimal degree of adverse tissue reaction.

REFERENCES:
patent: 4032993 (1977-07-01), Coquard et al.

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