Quaternary ammonium alkylene diphosphonate anti-calculus agents

Drug – bio-affecting and body treating compositions – Dentifrices – Ammonia – amine – or derivative thereof

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26050112, A61K 722, C07F 938

Patent

active

042084016

ABSTRACT:
Quaternary ammonium alkylene diphosphonates useful as stain-inhibiting, anti-calculus agents, compatible with cationic antimicrobials; the process of preparing said quaternary ammonium diphosphonates; and compositions containing an effective anti-calculus amount of said quaternary diphosphonate admixed with a dental or oral carrier. These compounds are particularly effective in inhibiting tooth staining caused by cationic antimicrobials.

REFERENCES:
patent: 2542886 (1951-02-01), Wach
patent: 2774786 (1956-12-01), Erickson
patent: 3925543 (1975-12-01), Donahue
patent: 4054598 (1977-10-01), Blum et al.
Gross et al., J. Prakt. Chem., 318(l), pp. 116-126, 1976.

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