5-Aryl-1-(2-oxazolin-2-yl)-1H-1,4-benzodiazepines and related co

Details 5-Aryl-1-(2-oxazolin-2-yl)-1H-1,4-benzodiazepines and related co 5-Aryl-1-(2-oxazolin-2-yl)-1H-1,4-benzodiazepines and related co

1979-04-03

1980-06-17

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239BD, 260333, 2602433, 2602455, 2602456, 544 53, 544 96, 544316, 544331, 548348, 424244, 424246, 424251, 424270, 424272, 424273R, 424275, 42424857, 42424854, C07D41704, C07D40304, C07D41304

Patent

active

042083273

ABSTRACT:
5-Aryl-1-(2-oxazolin-2-yl)-1H-1,4-benzodiazepines and related compounds having the formula ##STR1## wherein A is methylene or carbonyl; Z is oxygen, imino or thio; R.sup.1, R.sup.2, and R.sup.3 independently are hydrogen, halogen, trifluoromethyl or nitro; R.sup.4 is hydrogen or hydroxy; and n is positive integer from 1 to 3 inclusive are disclosed. These compounds are useful because of their central nervous system activity.

REFERENCES:
patent: 3136815 (1964-06-01), Reeder et al.
patent: 3371085 (1968-02-01), Reeder et al.
patent: 3481921 (1969-12-01), Field et al.
Sternbach, "Benzodiazpines", Raven Press (1973), pp. 1-26.
Lednicer et al., Organic Chemistry of Drum Synthesis, (1977), Chapter 18, "Benzodiazepines", pp. 363-371.
Szmuszkovicz et al., "Tetrahedron Letters", No. 39, pp. 3665-3668, (1971).

Affiliated with

Also associated with

Rating

5-Aryl-1-(2-oxazolin-2-yl)-1H-1,4-benzodiazepines and related co does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 5-Aryl-1-(2-oxazolin-2-yl)-1H-1,4-benzodiazepines and related co, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 5-Aryl-1-(2-oxazolin-2-yl)-1H-1,4-benzodiazepines and related co will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-474574