System and method for modulating the output of an implantable me

Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems

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A61N 1365

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active

057333122

ABSTRACT:
An implantable cardiac pacemaker is provided for delivering pacing pulses to a patient, where the pacing pulses are defined by at least two parameters. The pacemaker allows for transitioning of the two parameters from first values to second values in response to the patient's circadian rhythms, such as in response to the beginning and ending of a sleep cycle. Also provided is an implantable pacemaker for delivering pacing pulses to a patient where the pacing pulses are defined by at least one parameter. The pacemaker allows for selective transitioning of the parameter from a first value to a second value in response to the patient's circadian rhythms.

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Morris-Thurgood, Jayne, et al., "A Rate Responsive Pacemaker That Physiologically Reduces Pacing Rates at Rest," PACE, vol. 17, Part II, pp. 1928-1932 (Nov. 1994).
Bornzin, Gene A., et al., "Adjusting Heart Rate During Sleep Using Activity Variance", PACE, vol. 17, Part II, pp. 1933-1938, (Nov. 1994).
Chew, Paul H., et al, "Overnight Heart Rate and Cardiac Function in Patients with Dual Chamber Pacemakers", PACE, vol. 19, pp. 822-828, (May 1996).

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