Method of space charge control for improved ion isolation in an

Details Method of space charge control for improved ion isolation in an Method of space charge control for improved ion isolation in an

1994-01-10

1995-09-05

Berman, Jack I.

Radiant energy

Ionic separation or analysis

Methods

250283, 250292, 2502521, H01J 4942

Patent

active

054480612

ABSTRACT:
A method of using a quadrupole ion trap mass spectrometer for high resolution mass spectroscopy is disclosed. In the preferred embodiment, the space charge in the ion trap is controlled to high accuracy. This is done by using a prescan of the trap before each analytical scan, where the ionization parameters used in the prescan are not fixed, but rather are based on the previous analytical scan. The method is especially useful in connection with performance of high resolution MS/MS experiments of the type described in the inventor's prior U.S. Pat. No. 5,198,665.

REFERENCES:
patent: Re34000 (1992-07-01), Syka et al.
patent: 4771172 (1988-09-01), Weber-Grabau et al.
patent: 5198665 (1993-03-01), Wells
patent: 5381006 (1995-01-01), Wells et al.
patent: 5397894 (1995-03-01), Wells et al.

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