N-derivatives of (phenylethyl-.beta.-ol) amine, a process for th

Details N-derivatives of (phenylethyl-.beta.-ol) amine, a process for th N-derivatives of (phenylethyl-.beta.-ol) amine, a process for th

1993-07-13

1995-09-05

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514471, 514473, 546283, 549495, A61K 3144, A61K 3134, C07D30712, C07D30714

Patent

active

054479428

ABSTRACT:
The invention relates to a N-(2,4- or 2,5-disubstituted tetrahydrofuryl alkyl)-N-(phenylethyl-.beta.-ol)amine derivative, under a racemic or enantiomer form, of general formula I ##STR1## wherein R represent various radicals and n is of from 1 to 10, to a process for the preparation of said derivative, and to pharmaceutical compositions comprising the same.

REFERENCES:
Thompson, A. S. et al., "Conversion of a Silylated Hemiacetal into an a-Bromoether Using Trimethylsilylbromide", Tetrahedron Letters, vol. 31, No. 48, pp. 6953-6956 (1990).
Konzett and Rossler, "Versuchsanordunung zu Untersuchungen an der Bronchialmuskulatur", Pharmakologischen Institute der Universitate Wien, 1940.
Chandrasekharan, J. et al., "Diisopinocampheylchloroborane, a Remarkably Efficient Chiral Reducing Agent for Aromatic Prochiral Ketones", J. Org. Chem., 1985, 50, 5446-5448.
Collin et al., "Saligenin Analogs of Sympathomimetic Catecholamines", Journal of Medicinal Chemstry, vol. 13, No. 4, 1970, pp. 674-680.

Affiliated with

Also associated with

Rating

N-derivatives of (phenylethyl-.beta.-ol) amine, a process for th does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-derivatives of (phenylethyl-.beta.-ol) amine, a process for th, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-derivatives of (phenylethyl-.beta.-ol) amine, a process for th will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-472973