Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1994-10-11
1995-09-05
Cintins, Marianne M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514143, 514144, 514148, A61K 3166
Patent
active
054479231
ABSTRACT:
Methods for the treatment of a human or lower animal subject having an H. pylori-mediated upper gastrointestinal disorder comprising administering to said subject a safe and effective amount of a diphenyl ether phosphate ester of the following formula: ##STR1## wherein n is an integer from 0 to 3, or a pharmaceutically-acceptable salt thereof.
REFERENCES:
patent: 3929903 (1975-12-01), Noguchi et al.
patent: 4894220 (1990-01-01), Nabi et al.
patent: 4980153 (1990-12-01), Jackson et al.
Kamat, N. V., "Biochemical Aspects of Periodontal Diseases: II. The Possible Significance of Calcuium Phosphorus and Alkaline Phosphatase in Human Saliva", Journal Indian Dent. Asso., vol. 50, pp. 171-178 (1978).
Glupczynski, Y. and A. Burette, "Drug Therapy for Helicobacter pylori Infection; Problems and Pitfalls" American J. Gastroenterology, vol. 85 pp. 1545-1551 (1990).
Graham, D. Y. and G. M. A. Borsch, "the Who's and When's of Therapy for Helicobacter pylori", American J. Gastroenterology, vol. 85, pp. 1552-1555 (1990).
Hiller, S., "A Better Way to Make the Medicine Go Down", Science, vol. 253, pp. 1095-1096 (Sept. 6, 1991).
Peterson, W. L., "Helicobacter pylori and Peptic Ulcer Disease" 324 New England J. of Medicine 1043 (1991).
Graham, D. Y., G. M. Lew, D. G. Evans, D. J. Evans, Jr., and P. K. Klein, "Effect of Triple Therapy (Antibiotics plus Bismuth) on Duodenal Ulcer Healing", Annals of Internal Medicine, vol. 115, pp. 266-269 (1991).
Wyle, F. A., "Helicobacter pylori: Current Perspectives", J. Clin. Gastroenterol, (Suppl. 1), S114-S124 (1991).
Blaser, M. J., "Helicobacter pylori: Its Role in Disease", Clinical Infectious Diseases, pp. 386-391 (1992).
Graham, D. Y., G. M. Lew, P. D. Klein, D. G. Evans, D. J. Evans, Jr., Z. A. Saeed, and H. M. Malaty, "Effect of Treatment of Helicobacter pylori infection on the Long-term Recurrence of Gastric or Duodenal Ulcer", Annals of Internal Medicine, vol. 116, pp. 705-708 (1992).
Borody, T. J., "Possibilities for Helicobacter pylori Suppression/Eradication", European Journal of Gastroenterology & Hepatology, vol. 4 (Suppl 2), pp. 537-538 (1992).
Graham, D. Y., "Treatment of Peptic Ulcers Caused by Helicobacter pylori" 328 New England J. of Medicine 349 (1993).
Hentschel, E., G. Brandstatter, and B. Dragosics, "Antibiotic Therapy Alone Eradicates Helicobacter pylori and Prevents Duodenal Ulcer Recurrence", Gastroenterology, vol. 105, p. 598 (1993).
CA: 233730d, Francis et al, Nov. 29, 1994.
Catrenich Carl E.
Nelson Dennis G. A.
Cintins Marianne M.
Criares T. J.
Rasser Jacobus C.
Suter David L.
The Proctor & Gamble Company
LandOfFree
Methods and compositions of diphenyl ether phosphate esters for does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and compositions of diphenyl ether phosphate esters for , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and compositions of diphenyl ether phosphate esters for will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-472858