Methods for chromosome-specific staining

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435243, 435805, 435820, 436501, 436 63, 436 64, 536 221, 536 231, 536 243, 536 2431, 536 2432, 536 2542, 935 77, 935 78, C12Q 168

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054478413

ABSTRACT:
Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogenous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes.

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