Certain pyrrolopyridine derivatives; novel CRF1 specific ligands

Details Certain pyrrolopyridine derivatives; novel CRF1 specific ligands Certain pyrrolopyridine derivatives; novel CRF1 specific ligands

1999-08-05

2000-10-17

Huang, Evelyn Mei

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514293, 514183, 51421205, 540479, 540583, 544328, 544331, 544333, 546 82, 546 87, 546113, A61K 31437, C07D47104, C07D47114, A61P 2524

Patent

active

061332828

ABSTRACT:
Disclosed are compounds of the formula: ##STR1## wherein Ar is optionally substituted aryl or heteroaryl

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Owens et al., "Physiology and Pharmacology of Corticotropin-releasing Factor," Pharm. Rev., Vo. 43, pp. 425-473 (1991).
Montgomery, et al. "The Use of Enamines I the Sythesis of Heterocycles," J. Het. Chem., vol. 9, pp. 1077-1079.
Zimmerman et al. "Pyrrolo[2,3-b]pyridines" Arch. Pharm. vol. 309, pp. 597-600.

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