2-substituted phenyl-benzimidazole antibacterial agents

Details 2-substituted phenyl-benzimidazole antibacterial agents 2-substituted phenyl-benzimidazole antibacterial agents

1997-09-05

1999-08-24

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514218, 514241, 514242, 514253, 514256, 514322, 514339, 514341, 514365, 514372, 514383, 514397, 514399, 514409, 514411, 514422, 514454, 514456, 540553, 540603, 544180, 544333, 544366, 546199, 546256, 5462734, 548202, 548205, 548214, 548255, 548411, 548440, 548518, 549406, 549414, 549460, A61K 3134, A61K 31415, C07D23306, C07D20706

Patent

active

059425326

ABSTRACT:
The invention relates to benzimidazole antibacterial compounds of the Formula I: ##STR1## as described herein, pharmaceutical compositions containing the compounds, and methods for their production and use. These compounds are effective in inhibiting the action of a bacterial histidine protein kinase and are useful as anti-infective agents against a variety of bacterial organisms, including organisms which are resistant to other known antibiotics.

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