Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1989-07-28
1990-08-14
Ford, John M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514649, 514576, 564321, 564342, 564344, 564345, 562 45, A61K 3135
Patent
active
049488139
ABSTRACT:
The invention relates to benzylketone phospholipase A.sub.2 inhibitors, pharmaceutical compositions containing them, and methods of treating phospholipase A.sub.2 -mediated conditions in mammals by administration of a therapeutically effective amount of such a benzylketone phospholipase A.sub.2 inhibitor. These compounds are also intermediates in the synthesis of other PLA.sub.2 inhibitors.
REFERENCES:
patent: 3979444 (1976-09-01), Lednicer
patent: 4239780 (1980-12-01), Wallach
Davis Zinna Northington
E. I. Du Pont de Nemours and Company
Ford John M.
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