Basically-substituted tricyclic pyrazoles useful as antiinflamma

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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42424852, 42424858, 424250, 424267, 424273P, 544140, 544371, 546199, 548369, C07D23156, A61K 31415

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active

041736346

ABSTRACT:
Compounds of the structure ##STR1## are provided, wherein n is 1, 2 or 3, m is 2, 3 or 4, X and Y may be the same or different and are hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio or trifluoromethyl, and B is di-lower alkylamino, piperidino, pyrrolidino, morpholino, or N-lower alkylpiperazino and pharmaceutically acceptable acid-addition salts thereof. These compounds have been found to be useful as antiinflammatory agents.

REFERENCES:
patent: 3926988 (1975-12-01), Krapcho et al.
patent: 3969527 (1976-07-01), Krapcho et al.
Hamilton, "J. Heterocyclic Chem.," vol. 13, (1976), pp. 545-553.

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