Method for manufacture of hollow fiber membrane type artificial

Coating processes – Interior of hollow article coating – Removing excess coating material

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422 48, 21032181, 2103219, 21050023, 21050024, 261122, 261DIG28, 128DIG3, A61M 114

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049718363

ABSTRACT:
A hollow fiber membrane type artificial lung and a method for the manufacture thereof. The artificial lung comprises a housing, a hollow fiber bundle positioned in the housing and formed of a multiplicity of gas-exchange hollow fiber membranes, a first fluid chamber defined by the external surfaces of the hollow fiber membranes and the internal surface of the housing, a first fluid inlet and a first fluid outlet both communicating with the first fluid chamber, partitions supporting in place the opposite ends of the hollow fibers and provided at the inner face of the housing, and a second fluid inlet and a second fluid outlet allowed to communicate with the empty spaces inside the hollow fiber membranes, which artificial lung is characterized by the fact that the hollow fiber membranes are produced by causing porous hollow fiber substrates which have through micropores distributed in the walls thereof to be treated with silicone oil so that the silicone oil will block up said micropores without forming a silicone oil layer on the internal surfaces of the walls of the porous hollow fiber substrates.

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Murphy et al., "Laboratory and Clinical Experience with a Microporous Membrane Oxygenator", Trans. Am. Soc. Artil. Organs, vol XX, 1974, pp. 278-283.

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