Process for the preparation of nitrophenyl hydroxy substituted a

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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568939, C07C 3304

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active

042040787

ABSTRACT:
Nitrophenylacetylene and certain precursors to nitrophenylacetylene are prepared in improved yields by reacting a nitrobromobenzene with a substituted terminal acetylene compound containing at least three carbon atoms and a hydroxy group on the carbon atom adjacent to the acetylene group in the presence of a dialkyl or trialkyl amine solvent and a catalyst system consisting of a palladium complex containing two halogen moieties and two tri-substituted phosphine moieties and some excess trisubstituted phosphine compounds.

REFERENCES:
patent: 4016214 (1977-04-01), Douglas et al.

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