Prostane derivatives

Details Prostane derivatives Prostane derivatives

1978-05-30

1980-05-20

Killos, Paul J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

560 21, 560 61, 560 55, 560 56, 560 59, 560 75, 260408, 260410, 2604105, 260413, 260404, 2604045, 2604109R, 562471, 562465, 562435, 562466, 562469, 562478, 424309, 424318, 424317, C07C17700

Patent

active

042040019

ABSTRACT:
The disclosure relates to .omega.-aryl substituted .omega.-nor prostaglandin analogues bearing an oxygenated function at C-10, such as a hydroxy radical, or a 9,10- or 10,11-epoxide. A typical compound is 16-(3-chlorophenoxy)-9.alpha.,10.beta.,11.alpha.,15.alpha.-tetrahydroxy-17 ,18,19,20-tetranor-5-cis,13-trans-prostadienoic acid. Also disclosed are chemical processes for the manufacture of said compounds, pharmaceutical and veterinary compositions containing said compounds, and a method of achieving luteolysis in mammals by the use of such compounds.

REFERENCES:
Derwent Abst. 82849Y/46 ZA 7604-010 01/09/77.
Derwent Abst. 83046X/45 BE 841.138 26/10/76.
Derwent Abst. 17872T-B BE 772147-Q 03/03/72.

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