Method of reducing reperfusion injury with imidazol-2-thiones

Details Method of reducing reperfusion injury with imidazol-2-thiones Method of reducing reperfusion injury with imidazol-2-thiones

1989-12-11

1991-03-12

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142358, 514255, 514326, 514392, A61K 3144, A61K 31535, A61K 31495, A61K 31415

Patent

active

049993658

ABSTRACT:
Certain imidazol-2-thiones are reported to reduce reperfusion injury which is the injury which occurs when molecular oxygen is reintroduced into an ischemic tissue. These compounds could be used to prevent much of the damage which occurs to the heart of a heart attack victim.

REFERENCES:
patent: 4367236 (1983-01-01), Grisar et al.
patent: 4405628 (1983-09-01), Dage et al.
patent: 4405635 (1983-09-01), Schnettler et al.
patent: 4410540 (1983-10-01), Schnettler et al.
patent: 4418071 (1983-11-01), Schnettler et al.
patent: 4532250 (1985-07-01), Stout et al.
patent: 4552880 (1985-11-01), Dage et al.
patent: 4556665 (1985-12-01), Erhardt et al.
R. C. Smith, J. C. Reeves, R. C. Dage, and R. A. Schnettler, Biochemical Pharmacology 36(9), 1457 (1987).
J. M. McCord, New Engl. J. Med. 312, 159 (1985).
Chemical Abstracts, vol. 101, No. 211047 (1984), abstracting S. Maeda, et al., Chem. Pharm. Bull., Tokyo 32(7), 2536 (1984).
Chemical Abstracts, vol. 90, No. 64361j (1979), abstracting Japanese Patent Appln. No. 78 52,422, published Oct. 22, 1976, T. Endo, et al., inventors.
Chemical Abstracts, vol. 87, No. 152201a (1977), abstracting Japanese Patent Appln. No. 77 46,074, published Oct. 11, 1975, M. Miyoshi, et al., inventors.

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