4-oxo-pyrido[2,3-d]pyrimidinone derivatives

Details 4-oxo-pyrido[2,3-d]pyrimidinone derivatives 4-oxo-pyrido[2,3-d]pyrimidinone derivatives

1985-10-16

1987-06-30

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544279, A61K 31435, C07D47104

Patent

active

046771085

ABSTRACT:
4-Oxo-pyrido[2,3-d]pyrimidine derivatives are herein described as well as processes for their preparation.
These compounds possess valuable pharmacological properties. As calcium antagonists they exert vasospasmolytic, vasodilatory, and antihypertensive activities. Surprisingly some of the compounds also have the effect of increasing contractility. They are therefore particularly suited for the treatment of vascular diseases.

REFERENCES:
patent: 4361700 (1982-11-01), Purcell et al.
patent: 4560753 (1985-12-01), Lesher et al.
Gorlitzer et al., Arch. Pharm. (Weinheim), vol. 314, pp. 938-949, (1981).

Affiliated with

Also associated with

Rating

4-oxo-pyrido[2,3-d]pyrimidinone derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 4-oxo-pyrido[2,3-d]pyrimidinone derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 4-oxo-pyrido[2,3-d]pyrimidinone derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-447771