Rehydratable antacid composition

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Derived from – or present in – food product

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424158, A61K 3308

Patent

active

046769846

ABSTRACT:
An rehydratable antacid composition of magaldrate gel and a process for preparing same are described by the invention. The composition is prepared from and contains precipitated and undried magaldrate gel, a polyhydric alcohol and fluidizing amounts of a first and second fluidizer. One fluidizer is provided by an aluminum hydroxide gel having colloidal properties and the second by a pharmaceutically acceptable citrate ion source including citric acid. The process and composition are characterized in providing rehydratable antacid composition which when admixed with water forms a fluid, resuspendible, pharmaceutically elegant suspension possessing high antacid capacity and stability at even elevated magaldrate concentrations in addition to the ability to fluidize stiff, paste-like magaldrate gel cakes.

REFERENCES:
patent: 4112072 (1978-09-01), Rubino et al.
patent: 4115553 (1978-09-01), Rubino et al.
patent: 4117116 (1978-09-01), Buehler et al.
Handbook of Nonprescription Drugs, Fifth edition, p. 16, Amer. Phar. Assoc., Wash. D.C.

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