Thermoplastic polyurethane anticoagulant alloy coating

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424423, 514 24, 514 56, 514822, 514929, 523112, 128DIG22, 604304, C08L 510, A61K 3175

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046769757

ABSTRACT:
An antithrombogenic thermoplastic polyurethane product and process for preparing the same which comprises a substrate and at least one layer of a polyurethane alloy complex comprising a thermoplastic polyurethane and completely dispersed therein a preformed complex of an antithrombogenic material ionically bonded with a quaternary ammonium compound.

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patent: 3844989 (1974-10-01), Harumuya
patent: 3846353 (1974-11-01), Grotta
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patent: 4118485 (1978-10-01), Eriksson et al.
patent: 4302368 (1981-11-01), Dudley et al.
patent: 4349467 (1982-09-01), Williams et al.
Larm et al, "New N.m. Thrombogenic Surface Prepared by Selective Covalent Binding of Heparin . . . ", Biomat., Med Dev., Art., Org. 11 (283), pp. 161-173 (1983).
Grode, G. A. et al., J. Biomed. Mat. Res. Symp. No. 3, pp. 77-84, (1972).

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