Process for the preparation of N,N'-disubstituted guanidines

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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C07C12800

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048989789

ABSTRACT:
A process for the preparation of aromatic N,N'-disubstituted guanidines is described in which the corresponding aromatic N,N'-disubstituted thioureas are reacted with ammonia and oxygen or with an oxygen-containing gas, in the presence of a solvent and elements acting as catalysts having atomic numbers 21 through 30 in the Periodic Table or the lanthanides or the salts, oxides or complexes thereof.

REFERENCES:
patent: 1630769 (1927-05-01), Scott
Chemical Abstract 92:94093g, Hungarian Teljes 17.165.
Chemical Abstract 99:212248f.
Noncondensed Aromatic Compounds, vol. 63, p. 35, Col. 1734, "Diphenyguanidine".
W. Theieheimer, "Synthetic Methods", vol. 25 (1971), No. 323.
Ullmanns Encyclopedia, Fourth Edition, vol. 12, pp. 416, 417 and 420.

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