Tricyclic benzimidazole compounds, pharmaceutical compositions a

Details Tricyclic benzimidazole compounds, pharmaceutical compositions a Tricyclic benzimidazole compounds, pharmaceutical compositions a

1988-01-15

1990-09-04

Rivers, Diana G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142245, 5142285, 5142298, 5142328, 514253, 514250, 514258, 514267, 514293, 544 60, 544 32, 544101, 544117, 544234, 544238, 544179, 544251, 544345, 544394, 546 82, A61K 31505, C07D48704, C07D47104

Patent

active

049544985

ABSTRACT:
The present invention provides tricyclic benzimidazoles of the formula: ##STR1## wherein R.sub.1 is a phenyl radical of the general formula: ##STR2## wherein R.sub.2, R.sub.3 and R.sub.4 can be the same or diferent as in claim 1. For A, B, C and D are understood those compounds where one or two of A, B, C or D are nitrogen. These compounds are useful to inhibit the aggregation of thrombocytes and erythrocytes, lower blood pressure and can increase the power of the heart.

REFERENCES:
patent: 4352931 (1982-10-01), Cuny et al.
patent: 4695567 (1987-09-01), Mertens et al.
Wiemer et al., J. Org. Chem., vol. 41, No. 18, pp. 3051-3053 (1976).
Keyser et al., J. Org. Chem., vol. 41, No. 22, pp. 3529-3532 (1976).
Alkhader et al., Chemical Abstracts, vol. 91: 123697u (1979).
Schneller et al., Chemical Abstracts, vol. 94: 192283e (1981).
Kumar et al., Chemical Abstracts, vol. 97: 38906r (1982).
Schneller et al., Chemical Abstracts, vol. 101: 230483t (1984).
Stevenson et al., Chemical Abstracts, vol. 104: 109572e (1986).
Rodgers et al., Chemical Abstracts, vol. 106: 156415g (1987) abstract of Monatsh. Chem., vol. 117(6-7), pp. 879-882 (1986).

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